Marija Milosevic (asker) Apr 3, 2023:

Hvala Milane na odgovoru. Imala sam kad je PD progressive disease, ali pomislila sam da je ovde možda neki lek kao što je neko napisao. Neću zatvoriti ovo pitanje dok ne dobijem tačno od te klinike.

Milan Nesic Mar 30, 2023:

Clear As Day 1)

Čak i ako pretpostavimo da je "with PD" u smislu "treated with CHT [and] PD" (a nije) i da je (SAMO) "PD" zapravo "PD-1" (a - nigde i nikada - nije) to opet nema smisla, jer se za lečenje malignih oboljenja koriste PD-1 inhibitori, a ne sâm protein PD-1;

2)

Ako u tekstu jasno kaže "Restaging control was performed and revealed a massive mass…" i ako je "restraging":
"restaging
(ree-STAY-jing)
A process used to find out the amount or spread of cancer in the body if it comes back or gets worse after treatment. Restaging may also be done to find out how the cancer responded to treatment. [...]"
https://www.cancer.gov/publications/dictionaries/cancer-term...

ja stvarno ne vidim šta tu više ima nejasno da bude u odnosu na "PD" (progressive disease, tj. "A standard way to measure how well a cancer patient responds to treatment. It is based on whether tumors shrink, stay the same, or get bigger."). #zbunj

Milan Nesic Mar 30, 2023:

anti-PD-L1 antibody ≠ PD-1 "Significance of PD-L1 Expression in Tongue Cancer Development
[...]
The subsequent suppression of immune function by PD-L1 binding would lead to promotion of tumour growth and metastasis. Treatment using anti-PD-L1 antibody results in inhibited binding of PD-L1/PD-1 and prevents immune evasion, allowing the immune system to attack cancer cells.1-3 In 2014, the cancer immunotherapy drug Opdivo (nivolumab), a PD-L1 inhibitor, was approved for the first time in Japan for malignant melanoma and non-small cell lung cancer."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299404

"PD-1
A protein found on T cells (a type of immune cell) that helps keep the body’s immune responses in check. When PD-1 is bound to another protein called PD-L1, it helps keep T cells from killing other cells, including cancer cells. Some anticancer drugs, called immune checkpoint inhibitors, are used to block PD-1. When this protein is blocked, the “brakes” on the immune system are released and the ability of T cells to kill cancer cells is increased."
https://www.cancer.gov/publications/dictionaries/cancer-term...

Marija Milosevic (asker) Mar 29, 2023:

Still confused Hvala svima , na sve ovo sam i ja naišla i nisam bila sigurna, a klijent kaže da ostavim tako PD jer je primio hemoterapiju u inostranstvu! Mene međutim dalje kopka da li se odnosi na progressive disease, programmable death ili pakitakesel…

Vesna Savić Mar 29, 2023:

Proverite s klijentom Možda je najbezbednije proveriti s klijentom jer ovako samo bacate graške...

Milan Nesic Mar 28, 2023:

Marija, na koje ste opcije dosad naišli?